S&F 1: Cells (MS) – Science with Evie

Life Science, M&E 2: Metabolism (MS), M&E 3: Cellular Respiration (HS), M&E 4: Aerobic/Anaerobic Resp. (HS), S&F 1: Cells (MS), S&F 2: Cell Function (MS)

Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity

October 13, 2022October 13, 2022 GwynneL.

https://doi.org/10.1093/brain/awac222 Summary: Glioblastomas are incredibly deadly brain tumors. While there have been decades of research on curing these cancers, survival rates haven't increased much. Recently, a study out of Tel Aviv looked at what makes glioblastomas so resistant to treatment. Results showed that glioblastomas are protected and fed by astrocytes. Astrocytes are specialized glial cells… Continue reading Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity

Inheritance & Variation of Traits, Inheritance 2: Genes and Growth (MS), Inheritance 2: Role of DNA (HS), Inheritance 5: DNA Technology (MS), Life Science, Natural Selection & Evolution, NSE 1: Evolution Evidence (HS), NSE 2: Evolution Factors (HS), NSE 2: Taxonomy (MS), NSE 3: Embryology (MS), S&F 1: Cells (MS), S&F 1: DNA to Proteins (HS), Structure and Function

Cas4-like Protein in Giant Viruses

July 12, 2020July 12, 2020 GwynneL.

https://doi.org/10.1016/j.isci.2018.04.001 SUMMARY: Mimiviruses are giant viruses that co-evolved with eukaryotic hosts and virophages. Virophages are tiny viruses that hijack the viral factories giant viruses set up inside the host. Just as the eukaryotic host and virophages have evolved a sort of symbiotic relationship to defend against giant virus attacks, giant viruses have also evolved a… Continue reading Cas4-like Protein in Giant Viruses

Inheritance & Variation of Traits, Inheritance 1: Behavior and Reproduction (MS), Inheritance 2: Genes and Growth (MS), Inheritance 2: Role of DNA (HS), Inheritance 4: Population Genetics (HS), Inheritance 5: DNA Technology (MS), Interdependent Relationships in Ecosystems, IR 1: Ecosystem Interactions (MS), IR 3: Ecosystem Stability (HS), Life Science, Natural Selection & Evolution, NSE 1: Evolution Evidence (HS), NSE 2: Evolution Factors (HS), NSE 4: Adaption (HS), NSE 4: Fitness (MS), NSE 5: Natural Selection (MS), NSE 5: Population Flux (HS), S&F 1: Cells (MS), S&F 1: DNA to Proteins (HS), S&F 2: Cell Function (MS), Structure and Function

Amoebae, Giant Viruses, and Virophages

July 11, 2020July 11, 2020 GwynneL.

https://doi.org/10.3389/fcimb.2017.00527 SUMMARY: In 2003, scientists discovered that giant viruses infected amoebas. These giant viruses are so big that they were mistaken for bacteria for the longest time. It wasn’t until scientists realized they contained no ribosomal DNA that these organisms were reclassified as viruses. From there, even more giant viruses were discovered. Some of the… Continue reading Amoebae, Giant Viruses, and Virophages

Inheritance & Variation of Traits, Inheritance 2: Role of DNA (HS), Life Science, Non-NGSS Articles, S&F 1: Cells (MS), S&F 1: DNA to Proteins (HS), S&F 2: Cell Function (MS), S&F 3: Body Systems (MS), S&F 4: Stimuli Response (MS), Structure and Function

mRNA vaccines – a new era in vaccinology

June 30, 2020June 30, 2020 GwynneL.

https://www.nature.com/articles/nrd.2017.243 SUMMARY: Traditional ways of making vaccines include using antigens and weakened or dead pathogens. While these methods have worked for us in the past, their application is limited. They don’t work against cancers and tumors and they can be expensive to produce. Using mRNA vaccines is a new and versatile way to create vaccines.… Continue reading mRNA vaccines – a new era in vaccinology

Life Science, S&F 1: Cells (MS), S&F 2: Body Systems (HS), S&F 2: Cell Function (MS), S&F 3: Body Systems (MS), Structure and Function

Immune responses in COVID-19

March 24, 2020April 17, 2020 GwynneL.

Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic SUMMARY: This article review looks at what is already known about SARS and MERS and uses the data and clinical studies to discuss potential vaccines and treatments for the new coronavirus, SARS-CoV-2. Compared to SARS-CoV and MERS, SARS-CoV-2 has a much… Continue reading Immune responses in COVID-19

Chemical Reactions, CR 1: Determining Chemical Reactions (MS), CR 3: Evidence of Reactions (HS), CR 4: Driving Reactions (HS), HSus 4: Evaluating Solutions (HS), HSus 5: Showing Human Impact (HS), Human Sustainability, Inheritance & Variation of Traits, Inheritance 2: Genes and Growth (MS), Inheritance 2: Role of DNA (HS), Inheritance 3: Mutations (HS), Inheritance 3: Mutations (MS), Life Science, M&E 2: Anabolism/Catabolism (HS), Matter & Energy in Organisms/Ecosystems, Natural Selection & Evolution, NSE 1: Evolution Evidence (HS), NSE 2: Evolution Factors (HS), NSE 3: Trait Selection (HS), Physical Science, S&F 1: Cells (MS), Structure and Function

Using NAC Against Antibiotic Resistance Bacteria

December 29, 2019 GwynneL.

N-acetyl Cysteine Coated Gallium Particles Demonstrate High Potency against Pseudomonas aeruginosa PAO1 SUMMARY: Antibiotic resistant bacterial infections are on the rise, especially in hospitals. One of the culprits is the bacteria Pseudomonas aeruginosa (POA1). Researchers are quickly running out of antibiotics to use against resistant strains. The problem has reached the point where colistin, a… Continue reading Using NAC Against Antibiotic Resistance Bacteria